Disable pushState on a particular page

Is it possible to disable pushState on a given page? in my application has a question and answer game, and on this screen I do not want to let the physical button go back work.

No, it is not possible and it is not possible to prevent physical button work. But if you use cordova Android app, then it is possible by adding backbutton event listener:

document.addEventListener('backbutton', function (e) {
  e.preventDefault();
  return false;
});